BULLETIN 2 (2011)

March 18, 2011

Your Health Bulletin is information from scientific literature to make sense of the right choices for your health.  It is a reminder to consider periodic check-ups of your spine, joint mechanics and appropriate exercise.  Maintenance is better than repair!

 

Topics

  • Which foods inhibit inflammation

  • Which foods promote inflammation by understanding the eicossanoids

  • Glutathione- the most important anti-oxidant-we make it?

  • The piriformis –and low back pain, where is it ,how to stretch it

  • Review of low back exercise

 

From: Breaking news from Med page-Wednesday February 09, 2011

 

Diet Soda Tied to Vascular Risk, but With Caveats

 

LOS ANGELES — Drinking diet soda — but not regular soda — was associated with a greater risk of stroke, MI, or vascular death

 

Comment: regular soda is nothing to jump up and down about–should avoid this too.

 

There are numerous factors that are associated with stroke; it is really a lifestyle disease as most of our chronic disease is—- a matter of choice. One of the primary mechanisms is elevated blood pressure–hypertension–and one of the poorly understood causes of high blood pressure is the consumption of gluten containing foods that is bread, cookies, cakes, cereal etc that our culture promotes as part of a good diet—read on

 

Journal of Human Hypertension (2002) 16, 411–415 Reversible hypertension following celiac disease treatment: the role of moderatehyperhomocysteinaemia and vascular endothelial dysfunction

Coeliac disease is a readily reversible malabsorption syndrome that is associated with relative folate and vitamin B12 deficiency. These are essential cofactors needed for homocysteine metabolism, the lack of which cause an elevation in homocysteine level that in turn impairs the vascular endothelial function, which results in high blood pressure.  Treatment of coeliac disease was associated with reduction in homocysteine levels with parallel ‘normalisation’ of endothelial function and ‘cure’ of hypertension.

Treatment

 

Note The treatment is avoid gluten—period

 

Want More Efficient Muscles? Eat Your Spinach

 

By eating lots of vegetables our muscles work better due to more efficient use of oxygen—read on

 

Science Daily (Feb. 4, 2011) — After taking a small dose of inorganic nitrate for three days, healthy people consume less oxygen while riding an exercise bike. A new study in the February issue of Cell Metabolism traces that improved performance to increased efficiency of the mitochondria that power our cells.

 

The researchers aren’t recommending anyone begin taking inorganic nitrate supplements based on the new findings. Rather, they say that the results may offer one explanation for the well-known health benefits of fruits and vegetables, and leafy green vegetables in particular.

 

“We’re talking about an amount of nitrate equivalent to what is found in two or three red beets or a plate of spinach,” said Eddie Weitzberg of the Karolinska Institute in Sweden. “We know that diets rich in fruits and vegetables can help prevent cardiovascular disease and diabetes but the active nutrients haven’t been clear.”

 

Until recently nitrate wasn’t thought to have any nutritional value at all and that this component of vegetables might be toxic. But Weitzberg and his colleague Jon Lundberg earlier showed that dietary nitrate feeds into a pathway that produces nitric oxide with the help of friendly bacteria found in our mouths. Nitric oxide opens up our blood vessels to lower blood pressure, for instance.

 

“Among the more consistent findings from nutritional research are the beneficial effects of a high intake of fruit and vegetables in protection against major disorders such as cardiovascular disease and diabetes,” the researchers concluded. “However, the underlying mechanism(s) responsible for these effects is still unclear, and trials with single nutrients have generally failed. It is tempting to speculate that boosting of the nitrate-nitrite-NO pathway may be one mechanism by which vegetables exert their protective effects.”

 

As an interesting aside, Weitzberg says that the benefits of dietary nitrates suggest that powerful mouthwashes may have a downside. “We need oral bacteria for the first step in nitrate reduction,” he says. “You could block the effects of inorganic nitrate if you use a strong mouthwash or spit [instead of swallowing your saliva]. In our view, strong mouthwashes are not good if you want this system to work.”

 

Comment: Mitochondria are the structures in cells that make our energy from the food we eat. If we eat the wrong food they don’ work so well and poor mitochondrial function–poor energy– is involved in many of the chronic health problems/disease/ just unhealthy aging. By the way we need about 8-10 cups of veggies a day for numerous reasons—calcium/magnesium, fiber etc.

 

The best of the vegetables is the cabbage family especially kale – read Foods That Fight Cancer.

 

Eating Your Greens Could Prove Life-Saving If a Heart Attack Strikes

Science Daily (Nov. 14, 2007) — A diet rich in leafy vegetables may minimize the tissue damage caused by heart attacks, according to researchers at the Albert Einstein College of Medicine of Yeshiva University. Their findings suggest that the chemical nitrite, found in many vegetables, could be the secret ingredient in the heart-healthy Mediterranean diet.

 

Nitrite and its “chemical cousin” nitrate are important because of their role in producing nitric oxide gas. In 1986, researchers made the remarkable finding that nitric oxide produced by cells lining healthy arteries and plays a crucial role in cardiovascular health by dilating arteries and aiding blood flow. Damage to the artery lining (in atherosclerosis, for example) impairs nitric oxide production and leads to cardiovascular disease and, ultimately, to heart attacks and strokes.

 

Nitrite in the diet comes mainly from vegetables–celery, beets, and spinach, lettuce and other leafy types. Once absorbed in the bloodstream, nitrate circulates to the salivary glands where bacteria convert it to nitrite, which is then swallowed in our saliva.  Nitrite then accumulates and become stored in organs such as the heart, kidney and brain.

 

On average, due to copious consumption of vegetables, Europeans’ consume 76 mg of nitrite and nitrate daily compared with a 0.77 mg American intake–nearly a 100-fold difference. “This large intake of nitrite and nitrate poses no known risks and could certainly help explain why the Mediterranean diet is heart-healthy.

 

  • Adverse reactions to medications are common place due not only to the medication but also due to the fact that the reason for the use of the medication is not being corrected.  There is always another way and better way to deal with the problems of pain–obviously by correcting the mechanical problems of poor joint and muscle motion with manipulation and exercise and the other problems of allergies and mood/anxiety states by altering our food selection to reduce inflammation—read on

 

Drugs commonly taken for a variety of common medical conditions including insomnia, allergies, or incontinence negatively affect the brain causing long term cognitive impairment in older African-Americans, according to a study appearing in the July 13, 2010 print issue of Neurology, the medical journal of the American Academy of Neurology.

 

These drugs, called anticholinergics, block acetylcholine, a nervous system neurotransmitter, and are widely-used medical therapies. They are sold over the counter under various brand names such as Benadryl®, Dramamine®, Excedrin PM®, Nytol®, Sominex®, Tylenol PM®, and Unisom®. Other anticholinergic drugs, such as Paxil®, Detrol®, Demerol® and Elavil® are available only by prescription. Older adults most commonly use drugs with anticholinergic effects as sleep aids and to relieve bladder leakage problems.

“We found that taking one anticholinergic significantly increased an individual’s risk of developing mild cognitive impairment and taking two of these drugs doubled this risk.

 

“Simply put, we have confirmed that anticholinergics, something as seemingly benign as a medication for inability to get a good night’s sleep or for motion sickness, can cause or worsen cognitive impairment, specifically long-term mild cognitive impairment which involves gradual memory loss. As a geriatrician I tell my Wishard Healthy Aging Brain Center patients not to take these drugs and I encourage all older adults to talk with their physicians about each and every one of the medications they take,” said Malaz Boustani, M.D., IU School of Medicine associate professor of medicine, Regenstrief Institute investigator and IU Center for Aging Research center scientist.

 

Although this study, which was funded by the National Institute on Aging, looked at only African-Americans, both Dr. Campbell and Dr. Boustani believe future studies will find that the results are generalizable to other races.

 

Provided by Indiana University School of Medicine

 

Comment

 

In my observation the food we consume on a day to day basis is much more important regarding the function of our brain. Consider one of the top quoted research scientists in the world.

 

Dr. Bruce Ames, past head of the biochemistry dept UCLA, studied rats for cognitive function (memory and ability to learn). He placed old and young rats in a pool of water with a submersible platform and timed how long it took the rats to find the platform. The young rats found it right away. He then gave the old rats carnitine and lipoic acid, co-factors allowing mitochondria to function properly. Then the old rats found the platform just like the young rats. Mitochondria produce energy–ATP— Dr Ames hypothesized that the old rats suffered from cognitive impairment and that by giving them nutrients to improve energy that their brain would function more like young rats—as demonstrated.

 

Since Dr Ames original research much has been learned about mitochondria, and memory. Two anecdotes: one a lady in early 60’s for about 1 year having significant difficulty remembering familiar surroundings, names, phone numbers, grocery lists etc daughter observed that her mom was ‘in a fog’ was advised to remove high risk intolerant foods—within 3 days mom was lucid. Another gentleman in 70’s with similar memory difficulty as well as becoming socially withdrawn was advised to remove similar foods and had moderate improvement then added further nutrients to support mitochondrial function resulted in significant improvement in 2 weeks.

 

Note that one of the primary food groups removed was gluten containing foods. The 2 following papers reveal the association of CD with memory problems (dementia). CD is only the tip of the iceberg of the problems with gluten containing foods.

 

Gastroenterology. 2005 Apr;128(4 Suppl 1):S92-7. Neurologic presentation of celiac disease.Celiac disease (CD) long has been associated with neurologic and psychiatric disorders including cerebellar ataxia, peripheral neuropathy, epilepsy, dementia, and depression.

 

Can J Gastroenterol. 2008 Nov;22(11):909-11. Neurological disorders in adult celiac disease. Celiac disease is associated with neuropathy, ataxia, dementia and seizure disorder.

 

Remember maintenance is easier than repair Do your exercise, eat food good for you

 

See you in the office

 

 

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